解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::We evaluated the prevalence of pathological visually evoked potentials (VEP) before the appearance of papilledema or other signs of elevated intracranial pressure in children suffering from craniosynostosis. In 52 children (19 girls, 33 boys, median age 7.6 months, mean age 7.6 months, range from 3 to 34 months) preop...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028746
更新日期:1998-12-01 00:00:00
abstract::During the last decade, rapid progress has been made in understanding the molecular pathways underlying the proliferation of both normal and neoplastic cells. The processes by which messages to initiate protein synthesis, cell cycle progression, and even cell death are transmitted from the cell surface or the cytoplas...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028729
更新日期:1998-11-01 00:00:00
abstract::Epidermoid cysts (ECs) are rare developmental lesions occurring anywhere along the central nervous system. Usually affecting adult patients, the occurrence of supratentorial dorsal cistern ECs has been reported in only 1 certain case of pediatric age. An additional pediatric case is presented. An 11-year-old boy had a...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028722
更新日期:1998-10-01 00:00:00
abstract::A series of neuroendoscopic third ventriculostomies in children less than 1 year old is reported. Twenty-seven patients underwent the procedure with 21 (77%) failing within a mean of 1.36 months of the procedure. Nineteen were subsequently shunted. The presence or absence of flow through the ventriculostomy and the si...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028693
更新日期:1998-08-01 00:00:00
abstract::A great majority of growing skull fractures occur in infancy and earlychildhood. Since the growth of brain is necessary as a driving force for these lesions to occur, almost all reported cases have been before the first 3 years of life. Although a number of uncommon locations, such as basiooccipital and skull base are...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000028682
更新日期:1998-07-01 00:00:00
abstract::In contrast to neoplasia, lesions of focal cerebral dysplasia are thought to be completed developmental processes of abnormal neuronal migration. We present three children with seizures resulting from brain lesions which pathologically demonstrate regions of both clearcut focal cortical dysplasia and also hypercellula...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028662
更新日期:1998-05-01 00:00:00
abstract::The epidemiology of pediatric brain tumor was studied in a 10-year period from 1986 to 1995 in Yamaguchi prefecture. The total number of pediatric brain tumors was 83, and the incidence was 2.5/100, 000/year, which did not change during the period. The sign most frequently seen was intracranial hypertension, whereas f...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028636
更新日期:1998-03-01 00:00:00
abstract::Intracranial and intraspinal ependymomas are uncommon tumors of the central nervous system. These tumors have a variety of imaging characteristics, some of which are fairly specific for ependymoma. We discuss the MRI features of ependymomas for each of the typical locations within the neuraxis, and provide MR imaging ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000028630
更新日期:1998-02-01 00:00:00
abstract::Hemifacial spasm (HFS), generally a disease of the elderly, is caused by vascular compression of the seventh nerve. Vascular compression is thought to result from atherosclerotic changes within the vessels of the posterior fossa, and therefore rarely presents in childhood. Here we describe our experience with 12 patie...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121260
更新日期:1997-11-01 00:00:00
abstract::To compare the functional development of the fourth ventricular outlet in the myeloschisis-Chiari malformation complex with that of a normal brain, the chronological development of the outlet in C57BL/6J non-neural-tube defect mouse embryos was examined as the first step. Then we compared the results with those of hom...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121248
更新日期:1997-10-01 00:00:00
abstract::We discuss the surgical approach used for and outcome in 11 infants (< or =3 years) who were treated at our institution for ependymomas arising in the cerebellar-pontine (C-P) angle. The median age of the group was 19 months (range: 6-26 months). Of these 11 patients, the initial surgery for 8 was performed at our cen...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121232
更新日期:1997-08-01 00:00:00
abstract::Thirty-six cases of pilocytic astrocytomas treated at the Childrens Hospital of Los Angeles from 1984 through 1995 were reviewed. The mean age at initial presentation was 8 years (range 15 months to 14 years). These patients were followed for an average of 5.5 years. No patient was given chemotherapy or radiation ther...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000121218
更新日期:1997-07-01 00:00:00
abstract::A case of an intracerebral juvenile xanthogranuloma (JXG) producing complex-partial seizures in a 13-year-old boy is presented. Although the child had no history of JXGs or a systemic histiocytic proliferative disorder, the histopathological and immunocytochemical studies of this lesion were identical to that of a cut...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000121212
更新日期:1997-06-01 00:00:00
abstract::Six patients with hydrocephalus who were treated with cerebrospinal fluid (CSF) shunts became refractory to serosal absorption of CSF. All were subsequently treated with ventriculo-gallbladder shunts. The surgical technique and long-term results were evaluated by retrospective review of the hospital records. Detailed ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121191
更新日期:1997-04-01 00:00:00
abstract::For over 60 years congenital kyphotic deformities of the spine have been categorized into two distinct groups, depending on the developmental defect. Those arising from a failure of formation of the vertebral bodies were classified as type 1, while those arising from a failure of segmentation were referred to as type ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121178
更新日期:1997-03-01 00:00:00
abstract::Cerebral sparganosis in childhood is very rare. Until 1996, 2 cases in children up to 15 years of age had been described. We report a case of cerebral sparganosis in a 6-year-old girl who presented with seizures. Sequential brain magnetic resonance imaging scans spaced over 4 months showed a lesion which migrated from...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000121171
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:Modern neuroimaging and intensive care permit precise delineation and specific treatment of head injury. Children sustaining cranial trauma associated with epidural hematoma (EDH) represent a heterogeneous group with a variety of clinical outcomes. Treatment consists of simple observation or surgical evacuati...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121144
更新日期:1996-12-01 00:00:00
abstract::A case is presented illustrating the usefulness of computerized tomography (CT) with 3-dimensional (3-D) reconstruction for evaluation of a subdental synchondrosis fracture in a child. Odontoid fractures in children less than 7 years of age occur at the subdental synchondrosis and are typically diagnosed with plain x-...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121135
更新日期:1996-11-01 00:00:00
abstract::Traumatic acute subdural hematoma is associated with high mortality in the pediatric population, yet the pathophysiology remains poorly understood. The objective of this study was to develop a pediatric model of acute subdural hematoma, and to evaluate the resultant histopathological changes in the brain. Ten 3-week-o...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121109
更新日期:1996-09-01 00:00:00
abstract::Most cerebrospinal fluid (CSF) shunts employed in the treatment of hydrocephalus include in their designs a pump mechanism that has been used in office practice as an indicator of whether the shunt is functioning properly; however, the pumping characteristics of shunts have been shown to correlate poorly with clinical...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121100
更新日期:1996-08-01 00:00:00
abstract::The occurrence and pattern of cervical spinal fusions have been assessed in 59 cases of Apert syndrome (acrocephalosyndactyly type 1). Radiological evidence of vertebral fusion either in progress or completed was observed in 37 (63%) of the cases. Fusion was limited to a single vertebral level in 18 cases and multiple...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121091
更新日期:1996-07-01 00:00:00
abstract::The unified theory, proposed by Pang et al., explains the embryogenetic mechanisms of all variants of split cord malformations (SCMs). All SCMs originate from one basic error occurring around the time when the primitive neurenteric canal closes. The basic error is the formation of an accessory neurenteric canal betwee...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121033
更新日期:1996-01-01 00:00:00
abstract::An intradural, intramedullary lipoma originating within the upper cervical cord with significant extension into the posterior fossa is reported in an infant. Two additional lipomas were found in the lumbar region. This constellation of findings represents the first description of multiple intradural, intramedullary sp...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121008
更新日期:1996-01-01 00:00:00
abstract::Brainstem gliomas (BSG) with intrinsic and extensive brainstem involvement continue to have a poor outlook despite current treatment approaches. Neuroimaging studies have aided in the differentiation of malignant brainstem tumors from more 'benign' subgroups. A Children's Cancer Group protocol evaluating outcome in ch...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121036
更新日期:1996-01-01 00:00:00
abstract::Radiotherapy has remained the mainstay of treatment for children with intrinsic, diffuse pontine tumors in spite of over 20 years of clinical trials attempting to validate the additional role of chemotherapy. Conventional phase II clinical trials conducted in patients with recurrent or progressive brainstem gliomas us...
journal_title:Pediatric neurosurgery
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1159/000121024
更新日期:1996-01-01 00:00:00
abstract::Diffuse pontine tumors are highly lethal and conventional therapy with irradiation provides long-term survival to a very small proportion of the patients. We have reported promising results using high-dose chemotherapy with autologous stem cell rescue in patients with recurrent high-grade astrocytomas in other anatomi...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121049
更新日期:1996-01-01 00:00:00
abstract::Posterior plagiocephaly secondary to lambdoid suture stenosis requires surgical release and repair to prevent progressive deformational changes associated with a suture stenosis. A surgical technique is described for release of the stenosed lambdoid suture and asterion region, followed by occipital reconstruction. Thi...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120895
更新日期:1995-01-01 00:00:00
abstract::This study was performed to compare the effects of continuous intrathecal baclofen infusion (CIBI) and selective posterior rhizotomy (SPR) on upper extremity (UE) spasticity and range of motion in children with cerebral palsy. Spasticity was assessed with the Ashworth scale of muscle tone and range of motion was evalu...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120941
更新日期:1995-01-01 00:00:00
abstract::Surgical reconstruction of cranial deformities and synostosis is occasionally accompanied by incomplete bone growth to cover all areas of cranial vault that have been exposed in the correction. The restrictive nature of some forms of synostosis require more bone in the repair than is available using the child's natura...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120959
更新日期:1995-01-01 00:00:00
abstract::Primary germ cell tumors confined to the optic nerves and chiasm without suprasellar extension are uncommon. These tumors appear similar to chiasmatic gliomas on both computed tomography and magnetic resonance imaging, potentially resulting in treatment errors if the diagnosis is based on radiologic criteria alone. Un...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120927
更新日期:1995-01-01 00:00:00
abstract::Ongoing research in the etiology of neural tube defects is increasingly being directed towards the molecular mechanisms at work in the formation of these complex lesions. We undertook to review the family history of patients in a large myelomeningocele/spina bifida clinic in an effort to identify genetic trends in the...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120977
更新日期:1995-01-01 00:00:00
abstract::A retrospective study of fractures of peritoneal catheters of ventriculoperitoneal shunts is described. Fracture of the peritoneal catheter accounts for 21.2% of shunt revisions. During the time period of January 1985 through July 1993, 401 PS Medical peritoneal catheters were installed and 23 fractures occurred. The ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120884
更新日期:1995-01-01 00:00:00
abstract::A 3-year-old boy with chronic papilledema, bilateral coronal synostosis and Pfeiffer syndrome underwent an orbitofrontal advancement. One month postoperatively, his papilledema had resolved, however, his vision progressively deteriorated over the ensuing 3 months to legal blindness. He had no symptoms or signs of incr...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120913
更新日期:1995-01-01 00:00:00
abstract::Between June 1989 and January 1994, 14 patients with recurrent (n = 11) or posttreatment residual (n = 3) medulloblastoma were enrolled in a program to evaluate the efficacy and toxicity of stereotactic radiosurgery (SR). Initial treatment consisted of subtotal surgical resection in 12 patients and complete surgical r...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120901
更新日期:1995-01-01 00:00:00
abstract::The epidemiology of cerebrospinal fluid (CSF) shunting in the United States is not well known; however, with recent national surveys, the prevalence, incidence, and cost of these procedures can be estimated. The prevalence of CSF shunts in the United States appears to be greater than 125,000, though this is likely an ...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120968
更新日期:1995-01-01 00:00:00
abstract::The cloverleaf skull deformity, or Kleeblattschädel, is a rare malformation caused by synostosis of multiple cranial sutures. This anomaly has been reported to carry a dismal prognosis both in terms of neurological outcome as well as cosmetic appearance if treatment is delayed. Due to the paucity of data concerning th...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000121296
更新日期:1995-01-01 00:00:00
abstract::The authors studied 58 patients, under 12 years of age, admitted to the Emergency Room of the Sao Paulo University Hospital between September 1987 and November 1991 with the diagnosis of traumatic extradural hematoma. Emphasis was given to the etiology of injury, the time interval from head injury to emergency room ev...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120814
更新日期:1994-01-01 00:00:00
abstract::Dermoids and epidermoids found at reoperation for tethered cord following myelomeningocele repair have been attributed to inadequate excision of cutaneous elements and 'implantation' in the repair site. This study reviews the pathological findings in excised placodes from fresh myelomeningoceles and specimens from tet...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章,评审
doi:10.1159/000120780
更新日期:1994-01-01 00:00:00
abstract::Changes in spinal curvature, scoliosis, kyphosis and lordosis are associated with the growth of patients with myelomeningocele. Previous investigators have stated that progressive developmental scoliosis is related to tethered spinal cord. In order to investigate the relationship of tethered spinal cord release to pro...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120762
更新日期:1994-01-01 00:00:00
abstract::In the older infant with a marked skull deformation from sagittal synostosis a midline craniectomy will not produce an optimal cosmetic result as the brain grows at a much reduced rate and cannot provide the impetus for passive correction of the deformity. An operative technique is described whereby the occipital prom...
journal_title:Pediatric neurosurgery
pub_type: 杂志文章
doi:10.1159/000120772
更新日期:1994-01-01 00:00:00